Serology in Lyme borreliosis is certainly not magic, but it helps in certain situations.
According to Béla Pál Bózsik M.D., the researcher who invented the DualDur methodology, experts have forgotten what it means in everyday practice that serology is an indirect diagnostic method. Seronegativity means that the method cannot demonstrate the presence of antibodies, for some reason or another. It does not mean that Lyme borreliosis is not there. One should know that there is a period in the early stage of illness when production of antibodies is low, but there is also such a period of low antibody production in the late stage. That is why it is very useful to have additional methods to demonstrate an active infection.