IgM Results and Direct Diagnostics in Lyme Disease Testing

Laboratory diagnosis of Lyme disease remains one of the most complex areas among infections. In clinical practice, the most commonly used serological tests measure the immune system’s response, primarily through the detection of IgM and IgG antibodies. However, scientific literature emphasizes that the interpretation of these results is not always straightforward. What Does IgM Mean…

Visualizing Live Borrelia Spirochetes with Advanced Microscopy

Accurate visualization of Borrelia spirochetes remains one of the most challenging aspects of Lyme disease research. While molecular and serological techniques are widely used, direct observation of living Borrelia organisms has historically been limited by the technical capabilities of conventional microscopy. A 2024 study published in Acta Microscopica presents the first application of an improved-resolution…

Bird–Borrelia Interactions: A Historical Review and Their Significance for Human Disease Ecology

This review article provides a comprehensive overview of the scientific understanding of bird–Borrelia interactions and their importance in the ecology of Lyme disease and other tick-borne infections. Drawing on more than a century of research, the authors trace the evolution of scientific knowledge from the earliest observations of Borrelia spirochetes to modern molecular and ecological…