Laboratory diagnosis of Lyme disease remains one of the most complex areas among infections. In clinical practice, the most commonly used serological tests measure the immune system’s response, primarily through the detection of IgM and IgG antibodies. However, scientific literature emphasizes that the interpretation of these results is not always straightforward. What Does IgM Mean…
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Accurate visualization of Borrelia spirochetes remains one of the most challenging aspects of Lyme disease research. While molecular and serological techniques are widely used, direct observation of living Borrelia organisms has historically been limited by the technical capabilities of conventional microscopy. A 2024 study published in Acta Microscopica presents the first application of an improved-resolution…
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A recently published study in the journal Animals provides important new evidence regarding the role of wild birds in the ecology of Lyme disease-causing bacteria. The research investigated the presence of Borrelia spirochetes in birds admitted to the Hortobágy Wild Bird Hospital and Sanctuary in Hungary and revealed surprisingly high rates of infection among several…
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This review article provides a comprehensive overview of the scientific understanding of bird–Borrelia interactions and their importance in the ecology of Lyme disease and other tick-borne infections. Drawing on more than a century of research, the authors trace the evolution of scientific knowledge from the earliest observations of Borrelia spirochetes to modern molecular and ecological…
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További olvasnivaló: Mélyebben érdekel a téma? DualDur – a direkt diagnosztika szerepe a Lyme-kór felismerésében
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The clinical trial to observe the efficiency of DualDur In Vitro Diagnostic System, which was developed to diagnose Lyme borreliosis, was taking place between 2019 and 2020. The data from the research was used to examine the performance, sensitivity and specificity of the system and the positive and negative predictive values. Out of the observed…
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Lyme disease is the most common vector-borne illness, which is typically transmitted by ticks – Ixodes species to be precise. The incidence of Lyme borreliosis is continuously increasing, which is caused by a number of factors. One of them is the transmission of Lyme disease from mother to foetus. Proven transplacental infection The first confirmed…
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Nothing, as you will see from the below evidence. Microscopy in diagnostics Microscopy played a great role in identifying unknown pathogens and it is still the first line of diagnostics in some diseases where the novel diagnostic tools failed first time or did not prove to be efficient in the long term. Examples are syphilis…
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Serology in Lyme borreliosis is certainly not magic, but it helps in certain situations. According to Béla Pál Bózsik M.D., the researcher who invented the DualDur methodology, experts have forgotten what it means in everyday practice that serology is an indirect diagnostic method. Seronegativity means that the method cannot demonstrate the presence of antibodies, for some reason or another.…
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